Daytryp Health

A Beginner’s Guide to Microdosing Psychedelics

It’s hard to know what someone means when they say they’re “microdosing” something. We’ve all had a friend or two proclaim the wonderful benefits of their microdosing journey. That said, what in the world is microdosing, and can we come up with a consensus for a definition? How much are you supposed to take when you’re microdosing psychedelics? 

All these questions get in the way of something that can be truly beneficial. We’re going to talk about how to microdose psychedelics today, exploring the benefits and strategies that people have had success with. 

We hope the ideas below serve as a useful reference if you happen to be exploring the idea of microdosing for yourself. 

Microdosing Psychedelics: What Does It Mean? 

When someone is “microdosing,” they’re ingesting very small amounts of a psychoactive substance on a regular basis. Most of the time, they take this medicine each day. 

The amount of the psychoactive substance and the purpose of use can vary a great deal, however. Some people might say they’re microdosing when they’re really taking enough of a substance to produce significant effects. 

You’ll experience effects some of the time, especially at first. For example, microdosing psilocybin might change your sensitivity to light for some time. That said, these effects shouldn’t be anything close to those of a standard dosage of psilocybin. 

Taking the same dosage day after day is thought to produce some general effects in your life, rather than serving as a temporary mood enhancer. It’s like the idea of SSRIs. 

If you’re taking medication for depression (SSRIs or SSNIs, in most cases), the effects don’t come right away. You need to give the drug a few weeks to integrate with your system, altering the production of dopamine or norepinephrine in your body. 

Microdosing can be approached in this way as well. 

How Much Is Enough? 

Because microdosing isn’t an exact science, it’s difficult to prescribe dosages. 

Anyone who gives you a specific dosage and swears by it might not be the most reliable source. This is because everyone’s body is different. Your sensitivity to psychedelics is key. 

The idea is to take an amount that falls below your threshold of perception. In other words, you should not be able to feel the effects of the psychedelic. Before you set yourself a dose, it’s wise to experiment with small dosages over the course of a few weeks. 

The range for psilocybin mushrooms is somewhere between 0.1 and 0.4 grams. A full-scale psilocybin experience is typically around 3 grams of mushroom. 

DO NOT use the same weight if you’re microdosing with other substances. 0.4 grams of LSD or DMT will produce much stronger effects. Those substances are also difficult to regulate because there isn’t as much research or approval. 

Psilocybin is certainly one of the more reliable options that people have had positive experiences with. 

Benefits of Microdosing Psychedelics

“If the dosage isn’t enough for you to experience, what is the point of taking the substance?”

The benefits come over time. In effect, the psilocybin turns into what’s called a “nootropic.” This is a substance that’s used as a supplement to improve different functions of the brain. Many people use nootropics to try and increase focus, for example. 

What about psilocybin and psychedelics as nootropics, specifically, though? 


There are numerous scientific studies that cite the value of macrodosing psychedelic mushrooms in efforts to treat mental illness and anxiety disorders. 

The challenge is that there isn’t much scientific evidence behind the idea of microdosing psychedelic mushrooms. This isn’t to say that it isn’t effective, only that the scientific community hasn’t taken much interest in it. 

As a result, it’s difficult to give a clear answer as to what will happen if you do it. Further, it’s tough to give specific advice on dosage, dosage intervals, and more. That said, there are a few things that people generally report when they’re going through a microdosing period. 

  • Brighter mood
  • Clearer head
  • Creativity
  • Focus
  • Anti-anxiety
  • Less mental chatter

The reasons that people have for microdosing are very similar to the reasons that they take other nootropics. Mushrooms are a natural alternative to those otherwise chemically crafted drugs, though. Further, many people have a familiarity with psilocybin, which makes them a little more comfortable using it as a substance for microdosing. 

How Does Microdosing Work? 

How can a person microdose effectively? 

It’s simple. All you need to do is have the substance, a scale, and a little determination. Try to measure out your daily dosages in advance, ensuring that all of them are the same size. 

Again, you need to do a little exploring as you try to figure out the perfect dose for you. Be sure to find a dose that’s subperceptual and doesn’t cause any noticeable effects. If you’re interested in taking enough to experience effects each day, that’s not “microdosing,” technically speaking. 

Then, simply take your dose in the morning. That’s all you have to do to get started!

Key Microdosing Tips

Do your best to keep tabs on the effect of your microdosing. By that, we mean jotting things down in a little journal, week-by-week. 

Maybe keep daily tabs of your mood, your thoughts, your creativity, energy, and more. Focus on the areas of yourself that drove you to start microdosing in the first place and follow one or two metrics that could indicate progress. 

For example, maybe you started to microdose because you were feeling extra anxious at work. When you start microdosing, rate your anxiety on a scale from 1 to 100 each day. 

Compile your data into a little graph or chart and see how things change over time. Account for other things in your life that could be causing or easing that anxiety as well. If you do this with one or two data points, you should be able to confidently say whether the microdosing has helped. 

Don’t Get Caught Up with Placebo

The placebo effect is what happens when we know we’re taking something for a particular purpose, so our body creates the desired response on its own. 

With microdosing, you might have hundreds of different purposes that you think the dose will serve. That could cause your brain and body to work their magic and produce different results. These results wouldn’t be specifically from the mushrooms, although they wouldn’t happen if you didn’t take them. 

People often use the placebo effect as an argument against things without scientific research. 

Our question is, why should that matter? If you’re taking medication and experiencing benefits from it, that’s a good thing. So, if you’re finding that you’re benefiting a great deal from microdosing, try not to pick away at whether the effects are placebo.

Just enjoy your improved health!

Learn Various Microdosing Options

Microdosing psychedelics doesn’t need to happen with just psilocybin. You can explore LSD, DMT, peyote, and more. The important thing is that you’re doing this in a responsible way.

With all of these, keep in mind that legal statuses vary, there are seldom ways to receive the same quality of substance, and, as a result, you put yourself in the way of various risks. 

In most cases, variability in quality reduces the reliability of your experience. For example, one type of LSD might be twice as potent as another, making it difficult for you to safely incorporate the substance into your lifestyle.

The best way to go about microdosing and learning how to incorporate it is by learning from the authorities on the subject. Our site has some good guides, filled with personal experiences and various resources to help you learn more.

Bottom Line: Should You Try It?

If you’re considering microdosing to enact a change in your life, it’s certainly something worth trying. That said, it’s important that you’re doing so in a careful way!

The spooky propaganda about psychedelic substances is almost entirely false. When used responsibly, these substances can be drivers of deep personal change and spiritual growth. 

That said, certain variables can make massive differences. Depending on who you are and your sensitivity to these substances, you might not be in the right place to start exploring. Further, there’s truly something to the old “set and setting” idea. 

The idea is that your mindset and the setting you’re in are the two most important pieces of any psychedelic experience. For (an extreme) example, you would have a much better time enjoying psilocybin on a placid hillside than you would in a room next door to a couple screaming at each other. 

Microdosing doesn’t produce intense experiences worth fretting over, but you still have to identify the proper dosage for yourself and go through a sort of experimental process. 

The point is, do your research! Set yourself up for success, and you have a real chance of using these substances to find some personal growth. 

Want to Learn More About Psychedelics?

We hope our look at microdosing psychedelics was useful to you. There’s a lot more to learn about how to microdose psychedelics, though. We’re here to help. 

Explore our site for more ideas on psilocybin, ketamine, psychedelic experiences, microdosing, and much more. 

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*Daytryp is a Pro Microdosing Community*

We support the careful use of psychedelics to foster creativity, focus and compassion. We allow our employees to microdose in the workplace.

Yvé Dizes

Tryp Guide

Grounded in decades of extensive training with shamans, yogis, and spiritual teachers, Yvé
leverages her innate ability to channel the quantum field to provide profound insight and
transformation for her clientele. Her work is deeply influenced by her daily meditation practice, esoteric research, quantum mechanics, and J.R.R. Tolkien… only partially a joke!

Yvé’s advocacy for Divine Neutrality inspired her exploration into the transformative potential of Ketamine therapy. She delights in her role as a Tryp Guide, where she creates and holds sacred space, promoting transformation through this unique modality. Graced with an amazing partner and soul community, Yvé is humbled and honored to share her life’s purpose with you.

Will Burkhart

Tryp Guide

Will has spent his life seeking truth and exploring the limits of what is possible. This has led him to many extreme experiences—Marine Corps combat veteran, US Army Airborne and Ranger schools, wilderness adventure racing, high altitude mountaineering, ultra-endurance events, holistic healing modalities, psychedelics, and coaching. 

Will is a Co-Active Certified Professional Coach and a High Flow Performance Coach. He specializes in integrative psychedelic coaching and facilitating psychedelic experiences. He is relentless in his passion to explore life’s magnificence.  It’s an ongoing journey and one he would be honored to share with you as a Tryp Guide.

Steve Judson

Tryp Guide

While everyone has a different path to happiness, the majority of people encounter comparable experiences along the way. Examples include honesty, kindness, compassion, generosity, concern for oneself, others, and nature; respect for life; a desire to make a good difference; and many more.

Steve’s involvement, acceptance, and advocacy of the use of entheogenic substances as sacraments for direct spiritual experiences is what has inspired him to work hard to create peace and harmony in both his own life and the lives of those around him.

Steve has made a commitment to rejuvenating his own spiritual life using humanist resources and a humanist perspective. With an emphasis on the mysticism of the unitive experience and the practical use of entheogenic rituals for learning about and developing human consciousness to create a direct connection to the Divine within, Steve has been studying and using a variety of transformational tools. Each has acted as a catalyst in his own consciousness, resulting in profoundly life-altering experiences that have gradually revealed Steve’s true self and pointed him in the direction of his true purpose in life.

Steve’s desire to be of service to others by coaching, mentoring, and guiding them through a shamanic methodology and the practical use of entheogenic rituals is the driving force behind his life’s work, passions, and interests.

Steve loves sharing the knowledge he has gained using many entheogenic sacraments and transformational tools that can help spark a shift in consciousness and result in a profound realization of one’s true nature. Steve also firmly endorses both the idea of cognitive liberty (the right to direct one’s own consciousness) and the safe and appropriate use of entheogenic sacraments for a direct spiritual experience.

Steve has put a lot of effort into learning about and developing the best techniques as a practitioner and guide to provide the right guidance, proper preparation, safe navigation, and holistic integration into the sacred work he performs, and he remains dedicated to his work through practice, mentorship, and study.


There is a prayer in Sanskrit, one of the oldest recorded languages dating back 7000–8000 years, that says, “Lokah Samastah Sukhino Bhavantu.” This means: “May all beings everywhere be happy and free. May the thoughts, words, and actions of my own life contribute in some way to that happiness and that freedom for all.” This is a truth Steve lives by every day.

Megan Schneider

Tryp Guide

Megan is passionate about holding a sacred space for others to explore healing connections between the mind, body, breath, and spirit. As a plant energy practitioner, essential oils specialist, and yoga teacher, she wholeheartedly believes in an individualized approach to health and the power of curating personalized integrative self-healing practices of your own. Megan creates space for others to explore the therapeutic benefits of psychedelic medicines, both from a physiological and metaphysical standpoint, while inspiring others remembrance of their divine beauty, purpose, and gifts. Through the art of intention, peaceful presence, and loving awareness she hopes to welcome you more deeply into accessing your innate power to heal from within.

Joel Newton

Tryp Guide

From a young age, Joel sought happiness in competitive sports, business, and relationships. Each accomplishment came with a fleeting sense of fulfillment causing another repeat of the same cycle. That same mysterious desire for acceptance led Joel to seek information in new and unfamiliar territories. Joel has found comfort in his study of past and current visionaries, such as Carl Jung, Dr. Richard Schwartz, Deepak Chopra, and Gabor Matè. Learning that love of oneself is the true path to peace. Joel honors medicines and substance along with meditation and self-care for the aid of self-discovery. He has found that nothing is more enjoyable than supporting others in their constant journey of growth. Healing himself and others has become his greatest gift and passion.

Nick Ghiz

Tryp Guide

Nick’s upbringing instilled in him the significance of giving, helping, and inspiring others. He understands that these invaluable gifts have the power to shift paradigms within one’s life. For him, being involved in someone’s transformative journey is a privilege. Deep within each of us lies the ability to discover peace and lasting happiness. Sometimes we just need someone to guide us along the way. Nick carries this responsibility close to his heart, knowing firsthand the vulnerability we experience when seeking help. He hopes to be a bright light throughout this magnificent adventure you are about to embark upon.

Stephanie Bernau


Tryp Guide

Stephanie is a registered nurse helping to guide individuals in their journey towards wellness. Raised in Pima, Arizona and graduating from her hometown college, she has over 9 years of experience in pediatric emergency and trauma medicine. With her passion for health and involvement in the fitness community, Stephanie became a fitness coach in 2017. Dedicated to her own personal project of “unbecoming” and healing, Stephanie went on to receive her Bachelor of Science in Nursing at Arizona State University in 2022, focusing on the evidence-based approach to integrating the mind, body, and spirit for optimal health and wellbeing. Stephanie is an advocate for integrative health and wellness, while honoring your journey by providing a compassionate and supportive space for healing. In her spare time you can find her exploring the sky with husband Jamie and their dog Coco.

Hanna Caldwell


Tryp Guide

Hanna is from a small town here in Arizona. From the time she was a child, community has been a huge part of her life. She believe in total wellness and healing through mind, body and soul. This been a theme in her life, especially as an ER nurse and a nurse here at the clinic. Hanna loves helping others and blending western and holistic medicine to help others live to their greatest potential.

Ann Berardi


Tryp Guide

Ann is a registered nurse with a passion for helping others find balance in wellness and health. After graduating with her BSN from Cleveland State University in 2013, she worked briefly as a progressive care cardiac nurse. During that time, she was trained in Usui Reiki and completed her master/teacher level training in 2014. She then devoted herself as a hospice nurse, supporting and coaching many individuals and their loved ones through the dying process. After several years, Ann transitioned her skills and desires to focus on helping individuals achieve optimal wellness with holistic therapies. She opened a small mobile IV infusion business in 2019, offering in-home infusion therapy focusing on prevention and health maintenance. She also became certified in medical aesthetics.
Her constant ambition as a nurse is in service and helping others activate their own healing for optimal wellness while living from their highest self. Her goal is to provide a calm and peaceful environment where individuals can relax into healing.
She grew up in Latrobe, Pennsylvania and has lived in sunny Arizona since 2015. She finds relaxation in the outdoors, hiking, kayaking, star-gazing and flying airplanes.

Alisia Malta


Tryp Guide

Alisia graduated from Arizona State University with a Bachelor of Science in Nursing in 2011. She has worked in both outpatient and inpatient settings during her 12 years as a RN. Her fascination with the human brain led her to become a specialist in Deep Brain Stimulation therapy. Alisia is also an artist and has been selling her work professionally for the last 10 years. Through several difficult life events, she experienced firsthand the healing power of creative expression. Her passions reside in health, psychology, art, and human connection. She is ecstatic to be part of the Daytryp team, and grateful for the opportunity to assist with the intentional use of psychedelic medicines for healing.

Nellie Bowers, RN


Tryp Guide

Nellietha (Nellie) has been in healthcare for 18 years. She graduated with a Bachelors in Science from Chamberlain College of Nursing in 2018. She grew up in a family that prioritized alternative medicine and witnessed firsthand the profound impact natural remedies have on physical and mental health. As someone who has personally experienced the transformative effects of psychedelics, she is passionate about helping others find relief and healing through these alternative therapies. In her free time, she enjoys her animals, gardening, and being out in nature.

Jeff Kaplan

Jeff was born and raised 25 miles north of Chicago, IL. He graduated from The University of Michigan in Ann Arbor in 1999 with a B.S. in Business Communications. Jeff has worked for several successful start-ups in the consumer and daily deal space, excelling in business development and customer service. He is a certified life-coach specializing in working with adolescents. As Daytryp’s Intake Coordinator, he takes great pride in being the first voice our clients hear when they call into the facility. He enjoys working on his spiritual self, doing voiceover work, spending time with his girlfriend in San Diego and taking his bulldog Walter on road trips across the country.

Dave Romanelli

Chief Vibe Officer

David Romanelli fuses ancient wellness practices with modern passions that give people accessible tools to overcome stress, focus their mind, and improve their relationships at work and home. David’s third book, Life Lessons from the Oldest and Wisest, is a reminder that countless professionals, parents, and partners have walked the earth before us. The book was inspired by his series of national events called DRINKS WITH YOUR ELDERS, that created a space for isolated elders to reengage with their community and share their life experiences with younger generations. His previous book, Happy is the New Healthy, was inspired by David’s friendship with a 111 year-old New Yorker. The book reached #1 on multiple Amazon and Apple Bestseller Lists.

Dave partnered up with Daytryp Health to create TRIPT, which is a psychedelic integration APP which is offered to all Daytryp clients.

Most recently, David was a featured voice on a new app from Calm, which brings peace of mind and healing techniques to the 1 of every 3 Americans touched by cancer. His daughter Cooper (aka SuperCooper) put leukemia in the rear view mirror and is David’s inspiration everyday to live with strength, passion, and joie de vivre. Throughout Cooper’s treatment, David found the power of psychedelic therapy as a profound way to heal the trauma and constant worry and reset to a positive path forward as parent, partner, and professional.. His 365 day platform, MEDITATE ON, compels his listeners to gain perspective on their journey and take time each day for reflection, quiet, and meditation. David has been featured in The New York Times, Food & Wine, Wall Street Journal, and Newsweek. You can learn more at

Furthermore, Dave is in charge of Daytryp Retreats, which brings people from all over the world to Phoenix, AZ for 3-4 day retreats to experience life-changing psychedelic journeys.

Dr. Joe Tafur


Medical Advisor / Tryp Guide

Dr. Joe Tafur has dedicated his career to exploring complementary and alternative approaches to health management, particularly Amazonian plant medicines. He completed a Post-Doctoral Research Fellowship at UCSD Department of Psychiatry, and worked as a Family Physician in the US before exploring indigenous medicine in South America (SA). He helped found Nihue Rao Centro Espiritual, a traditional healing center in the Peruvian Upper Amazon, and underwent apprenticeship in Traditional Amazonian Plant Medicine and Shipibo curanderismo. In 2017, Dr. Joe founded Modern Spirit, a 501c3 nonprofit focused on demonstrating the value of spiritual healing in modern healthcare. In 2019, he and his colleagues opened the Ocotillo Center for Integrative Medicine. Dr. Tafur is also a leader in his spiritual community and leads plant medicine journeys across the continent. Joe is also a best selling author with his book, The Fellowship of the River.

Rebekah Bohucki


Tryp Guide

Rebekah graduated from Arizona State University with a Bachelor of Arts in Chemistry, then went on to obtain a Bachelor of Science in Nursing from Grand Canyon University. After working as an RN in the hospital setting for 13 years, Rebekah stepped away to pursue a career more oriented towards holistic healing and treating the root cause of disease. Rebekah is passionate about the powerful healing abilities of psychedelics and plant medicine and believes that with the right tools and guidance, our mind and body have the innate wisdom and ability to heal from the inside out. Rebekah is also on her path to becoming a Priestess, which includes training in the sacred art of holding energetic space. On her free time, she loves being a mom to her two beautiful children, traveling the world, hiking, yoga, and reading.

Kathryn Kiser

Tryp Guide
Kathryn, also known as Kat, has a deep love for nature and animals and a passion for the great outdoors. She cherishes her children and her dog, and enjoys being silly and surrounded by loved ones. She loves laughing and feeling free. Kathryn prioritizes taking care of both her heart and loves the activities that she chooses daily. Her personal journey towards self-love has been a long and challenging one, with many ups and downs. She spent a lot of her life living in fear and suffering with a closed heart. Choosing to heal through her traumas and open her heart have been the best adventures yet. Kat chooses to be a student of life and will continue on this path. As a participant in your healing journey, she holds space for you to feel into your own love and to witness your growth and healing. From her heart to yours, she looks forward to supporting you on your journey.

Lauren Krison

Lead Tryp Guide & Operations Manager

Lauren is a Phoenix native. She graduated from Arizona State University Cum Laude with a Bachelor of Arts in 2007. After spending over a decade in corporate and start-up marketing, the burnout became unbearable, and she knew it was time to pivot to her true passion – wellness. From diet and lifestyle changes to subconscious reprogramming and psychedelic medicine, Lauren’s own wellness journey led her to discover healing modalities that transformed her life in every way imaginable. Her passion led her to the Institute for Integrative Nutrition where she graduated in 2021 as a Certified Integrative Nutrition Health Coach. As a Tryp Guide, Lauren is honored to hold space for others as they embark on a healing journey of their own.

Ajona Olsen

MSN, APRN, ANP-C, Medical Director

Tryp Guide

Ajona Olsen started her career in healthcare in 2001 as an RN in a hospital. She graduated from Arizona State University as a nurse practitioner in 2006, and worked in corporate medicine for fifteen years. In 2021, she began researching psychedelics as a powerful tool in healing and trained in Ketamine Assisted Psychotherapy. Ajona opened her own practice at the beginning of 2022 to serve those on a journey toward healing and, in turn, has found happiness in the healing for herself and her loved ones. Ajona met Chris Cohn, founder of Daytryp Health, in June of 2022. She is very excited to act as Medical Director and partner with the incredible team at Daytryp. Outside of work, Ajona is an avid yoga enthusiast and enjoys spending time with her family.

Quinn Snyder


Chief Medical Officer

Quinn graduated from the University of Arizona College of Medicine in 2007. In 2010, after studying under Andrew Weil and traveling to India to study plant-based medicines, he completed his residency in Emergency Medicine at Drexel University. Quinn has continuously practiced EM at some of the top Departments in and around Phoenix. He possesses leadership experience in Data Analytics, Quality, Operations, and Business Development. During the pandemic, he was the manager of the largest Emergency Department in Arizona, and his experience was the subject of interviews on CNN, PBS Newshour, BBC World News, NPR, The Washington Post, and The Guardian. He has used Ketamine in his clinical practice and is committed to the emerging field of psychedelic medicines for healing.

Chris Cohn


Founder & CEO

Chris was born and raised in Phoenix, AZ. He attended Brophy College Preparatory, then graduated from the University of Arizona. Chris later attained his Masters Degree, Magna Cum Laude, in Addiction Counseling from Grand Canyon University. In 2008, Chris founded Scottsdale Recovery Center and Arizona Addiction Recovery Center, two of the most well-known drug and alcohol rehabs in the state. In 2019, after exiting the rehab space, Chris took a deep dive into the incredible world of psychedelic and plant medicines for his own healing journey. Daytryp Health was birthed from Chris’s ongoing desire and passion to help people heal, recover, and thrive with the intentional and careful use of psychedelic medicines.

Rudy Montijo

MS, LASAC, Consultant/Integration Therapist
Tryp Guide

Rudy Montijo lends his expertise in operations and business development consulting for Daytryp. He received his undergraduate from the University of Arizona, a master’s degree in Addiction Counseling from Grand Canyon University, and Ketamine Assisted Psychotherapy training from Polaris Insight. Rudy worked under Daytryp’s founder and CEO, Chris Cohn, while operating and expanding Scottsdale Recovery Center from 2013-2014. He currently has an award-winning career in medical sales. He is a former D1 athlete, having played football at the University of Arizona. Rudy is a clinical therapist who is trained in ketamine-assisted psychotherapy, actively races on the Ironman triathlon circuit, and is a certified yoga instructor. After helping others, Rudy’s greatest love is his two children, River and Savanna.

Esther Mathers

VP Operations


Esther is a seasoned designer with over 25 years of experience in the creation, management and development of calming spaces. A passionate and driving force behind any project, she thrives when curating environments that foster relaxation and well-being for both the mind and body. In addition, Esther has a talent for providing holistic solutions with innovative ideas to persistent challenges. She was honored to be commissioned by the Founder and CEO of Daytryp Health, Chris Cohn, to design the interior of their flagship location. The opportunity has been life-changing, transformative, and inspiring on many different levels. Esther currently lives in Mesa, AZ with her two children and enjoys outdoor activities, particularly those involving water.